孙宪昀 博士 副研究员 |
研究方向 真菌发育与耐药机制及植物病害绿色防控
研究内容
主要从事真菌的发育调控、真菌的耐药机制与耐药进化方面的基础研究,开展植物病害绿色防控和有机废弃物资源化利用方面的研发工作。
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导师简介
导师姓名:孙宪昀 电话:010-64806036(O) 电子邮件:sunxy#im.ac.cn(请将#换为@) 通讯地址:北京市朝阳区北辰西路1号院3号 邮政编码:100101
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主要学习及工作经历
-- 工作经历 2009.5–至今 金沙集团优惠申请大厅,助研、副研究员 2015.2–2016.2 得克萨斯大学西南医学中心,访问学者 2008.5–2009.4 北京生命科学研究所,博士后 -- 学习经历 2004.8–2007.12 山东大学微生物学专业,博士学位 2001.9–2004.7 西南农业大学植物病理学专业,硕士学位 1997.9–2001.7 西南农业大学(现西南大学)植物保护专业,学士学位
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近年代表性研究论文(*通讯作者)
1. Hu C, Zhou M, Cao X, Xue W, Zhang Z, Li S*, Sun X* (2022). Coordinated regulation of membrane homeostasis and drug accumulation by novel kinase STK-17 in response to antifungal azole treatment. Microbiology Spectrum, 10: e00127-22. 2. Zhou M, Hu C, Yin Y, Wang J, Ye S, Yu Y, Sun X*, Li S* (2022). Experimental evolution of multidrug resistance in Neurospora crassa under antifungal azole stress. Journal of Fungi, 8: e198. 3. Lan N#, Ye S#, Hu C, Chen Z, Huang J, Xue W, Li S*, Sun X* (2021). Coordinated regulation of protoperithecium development by MAP Kinases MAK-1 and MAK-2 in Neurospora crassa. Frontiers in Microbiology, 12: e769615. 4. Sun X*, Wang F, Lan N, Liu B, Hu C, Xue W, Zhang Z, Li S (2019). The Zn(II)2Cys6-type transcription factor ADA-6 regulates conidiation, sexual development, and oxidative stress response in Neurospora crassa. Frontiers in Microbiology, 10: e750. 5. Xue W#, Yin Y#, Ismail F#, Hu C, Zhou M, Cao X, Li S, Sun X* (2019). Transcription factor CCG-8 plays a pivotal role in azole adaptive responses of Neurospora crassa by regulating intracellular azole accumulation. Current Genetics, 65(3): 735-745. 6. Gu X, Xue W, Yin Y, Liu H, Li S. Sun X*. (2016). The Hsp90 co-chaperones Sti1, Aha1, and P23 regulate adaptive responses to antifungal azoles. Frontiers in Microbiology, 7: e1571. 7. Sun X, Wang K, Yu X, Liu J, Zhang H, Zhou F, Xie B, Li S*. (2014). Transcription factor CCG-8 as a new regulator in the adaptation to antifungal azole stress. Antimicrobial Agents and Chemotherapy, 58(3): 1434-1442. 8. Sun X, Wang W, Wang K, Yu X, Liu J, Zhou F, Xie B, Li S*. (2013). Sterol C-22 desaturase ERG5 mediates the sensitivity to antifungal azoles in Neurospora crassa and Fusarium verticillioides. Frontiers in Microbiology, 4: e127. 9. Sun X#, Kang S#, Zhang Y#, Tan X, Yu Y, He H, Zhang X, Liu Y, Wang S, Sun W, Cai L, Li S*. (2013). Genetic diversity and population structure of rice pathogen Ustilaginoidea virens in China. PLoS ONE, 8(9): e76879. 10. Sun X, Zhu J, Bao L, Hu C, Jin C, Harris SD, Liu H, Li S*. (2013). pyrG is required for maintaining stable cellular uracil level and normal sporulation pattern under excess uracil stress in Aspergillus nidulans. SCIENCE CHINA Life Sciences, 56(5): 467–475.
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授权专利
1. 一株耐酸性解淀粉芽孢杆菌Kc-5及其应用. 专利号:ZL201910598477.7
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